Below are listed curernt postdoctoral openings within our deparments. Please contact the lab manager to inquire about applying.
Toxicology and Cancer Biology
Dr. John D'Orazio, Markey Cancer Center
Description: Post-doctoral position available in the laboratory of Dr. John D’Orazio in the NCI-designated Markey Cancer Center at the University of Kentucky. The laboratory is interested in molecular mechanisms that determine melanocyte susceptibility to malignancy with a long-term goal of developing rational melanoma-preventive agents. The current project will follow up on recent findings linking melanocortin 1 receptor (MC1R) signaling to DNA repair (Mol Cell. 2014 Jun 19;54(6):999-1011). Projects include mechanistic studies with clear translational scope.
Requirements: The ideal candidate will have expertise in cell culture, mouse work, protein, and mRNA analysis as well as molecular techniques.
To apply: Interested applicants should send their curriculum vitae and a short statement describing previous research experience, future goals, and contact information of three referees to email@example.com
Dr. Ying Liang, Markey Cancer Center
Position: Postdoctoral Scholar
Description: A post-doctoral or visiting scholar position is available to study hematopoiesis and hematologic malignancy. We are seeking self-motivated and independent researchers to investigate molecular mechanisms involved in the regulation of self-renewal and differentiation of hematopoietic stem cells in physiological, aging and malignant conditions. Our research team uses integrative approaches that involve cell and molecular biology, flow cytometry, imaging, sequencing and in vivo mouse models.
Requirements: Research experience in hematology and/or hematological malignancy. A good publication record in recognized peer-reviewed journals. Technical independence with mouse colony maintenance, multi-color flow cytometry, bone marrow (or stem cell) transplantation, in vitro stem/progenitor colony assay, and cell culture. Proficient in the following molecular biology techniques: Western blot, Co-IP, ChIP, Immunofluorescence, PCR, real-time PCR, cloning, retrovirus or lentivirus-based gene overexpression and knockdown. Meticulous at planning, executing, and organizing the results and keeping scientific record. Good written and verbal (English) communication skills.
To apply: Submit an application through UK's on-line portal.
Dr. Kate Zaytseva, Markey Cancer Center
Position: Postdoctoral Scholar
Description: A postdoctoral position is available in a laboratory of Dr. Yekaterina (Kate) Zaytseva at the NCI-designated Markey Cancer Center at the University of Kentucky, Lexington. Dr. Zaytseva’s laboratory investigates the role of de novo lipid synthesis in cancer cell survival and metastasis using multiple cancer models including genetically modified mouse models, patient-derived xenografts and primary cultures. The position is available July 1, 2016 for a highly motivated individual with interests in cancer biology and lipid metabolism. Candidates must have a PhD with a strong background in cell and molecular biology and a reputable publication history. Expertise in cancer research, lipid metabolism and animal work is preferred, but not required.
Requirements: Candidates should have experience in cell culture, molecular biology techniques (qRt-PCR, western blotting and etc), basic statistical analysis. A background in cancer cell signaling, cancer metabolism, and in animal work is preferred.
To apply: Submit an application, including the supplemental documents (CV, writing sample, academic transcript, at least 3 professional references, copy of diploma) through UK's on-line portal.
Dr. Jia Luo
Description: We have a postdoctoral position working in the area of brain development/CNS injury. The current position is for 1.5 years and the continuation is contingent upon the grant renewal and the performance of the candidate.
Requirements: The candidate needs to have research experience in animal handling, breeding and surgery. She/he is also required to have experience in primary cell cultures. She/he should have good background in neuroanatomy, neurochemistry and cellular/molecular biology.
To apply: Contact Dr. Luo via e-mail at firstname.lastname@example.org
Dr. Yadi Wu, Markey Cancer Center
Description: We are currently seeking a highly skilled and motivated postdoctoral researcher in signal transduction in cancer. The postdoctoral candidate will be involved in research to develop new strategies to targeting breast cancer metastasis. This will examine mechanisms of tumor metastasis.
Requirements: Applicants should have a doctoral-level degree with solid background of biochemistry, molecular and cellular biology. A strong publication record and communication skills are plus.
To apply: Contact Dr. Wu via e-mail at email@example.com
Dr. Changcheng Zhou, Saha Cardiovascular Research Center
Description: NIH-funded postdoctoral positions with competitive salaries and benefits are available to study the molecular mechanisms of cardiovascular disease and metabolic dysfunctions. Our laboratory mainly focuses on the role of NF-kB (J Exp Med, 2014) and nuclear receptor signaling (Mol Endocrinol 2015; JAHA2014) in the pathogenesis of cardiometabolic disease including obesity, diabetes, and cardiovascular disease.
Requirements: Doctoral degree in molecular biology, biochemistry or related field, and strong background in cell culture, biochemical and molecular biology techniques and small animal model systems. Preference will be given to candidates with research experience in studying lipid homeostasis and atherosclerosis. Ability to work both independently and cooperatively within a team is essential.
To apply: Applicants should send a CV, a brief research statement, and the names/contact information of three people who could provide letters of reference to Dr. Zhou via e-mail at firstname.lastname@example.org
Molecular and Cellular Biochemistry
Dr. Matthew S. Gentry, Center for Stuctural Biology
Position: Postdoctoral Fellow
Description: A postdoctoral position is available immediately in the laboratory of Dr. Matthew Gentry (https://biochemistry.med.uky.edu/users/msge222), in the Department of Molecular & Cellular Biochemistry and Center for Structural Biology in the College of Medicine at University of Kentucky. The successful candidate will carry out an independent project on the mechanisms of Lafora disease and neurodegeneration and/or proteins involved in reversible (de)phosphorylation of plant starch using structural biology and biophysical techniques. The lab has a strong record of high impact papers with multiple recent publications in Molecular Cell, The Plant Cell, and PNAS with funding from both the NIH and NSF. Competitive salary will be based on qualifications. The project is funded through 2020.
Requirements: Applicants should have a strong background in molecular biology, protein purification, enzyme assays, and protein crystallization. Experience with x-ray diffraction, x-ray collection, and x-ray crystal structure determination is a plus, but not required. The successful applicant will be a highly motivated individual with good communication skills, interest and experience in biochemistry/structural biology in the arena of cell signaling, will have a proven publication record, and the ability to work independently. The applicant must currently have a Ph.D. in Biochemistry or a related field.
To apply: E-mail a single PDF containing a CV, 1-2 page summary of past research accomplishments, and contact information for three references to email@example.com with the subject heading “postdoc.”
Cardiac Physiology and Signal Transduction
Dr. Jon Satin and Dr. Doug Andres, Saha Cardiovascular Research Center
Position: Postdoctoral Position
Description: One NIH funded Post-doctoral position available immediately to study small G-protein regulation of L-type calcium channel current. We are seeking self-motivated ambitious researchers to investigate molecular mechanisms of calcium entry and their role in health and disease. The focus will be on the characterization of novel G-protein signaling pathways that are involved in Ca2+ channel regulation of cardiovascular function. Our research team uses an integrative approach that involves cell and molecular biology, electrophysiological, and in vivo mouse studies.
Requirements: Self-motivated individuals with a Ph.D. or equivalent advanced degree are encouraged to apply. The ideal candidate must have a solid publication record and evidence of excellent skills in molecular and cellular physiology. Previous experience with cardiomyocyte cell culture, lenti- or retro-viruses, or electrophysiology is preferred. Salary is competitive and includes benefits. Applicants should submit a resume and contact information for three references.
To apply: E-mail application materials with heading "postdoc" to firstname.lastname@example.org and email@example.com